Helena’s character, Dr Serena Kogan was dying of unspecified cancer in 2003. This required Helena to wear bald-cap prosthetics to emulate the effects of chemotherapy. Mike Smithson was the man behind the make-up.
Early concept art shows how Helena’s character might have looked had the original scripts not been leaked. The original ending, which had already been shot, saw Helena wearing a blond wig and tight silver dress. Dr Serena Kogan would have been revealed as a Cyborg, but this was entirely written out of the alternative ending. Helena instead appeared as a brunette hologram.